Journal article
Modelling associations between neurocognition and functional course in young people with emerging mental disorders: a longitudinal cohort study
JJ Crouse, KM Chitty, F Iorfino, JS Carpenter, D White, A Nichles, N Zmicerevska, AJ Guastella, EM Scott, RSC Lee, SL Naismith, J Scott, DF Hermens, IB Hickie
Translational Psychiatry | SPRINGERNATURE | Published : 2020
Abstract
Neurocognitive impairment is commonly associated with functional disability in established depressive, bipolar and psychotic disorders. However, little is known about the longer-term functional implications of these impairments in early phase transdiagnostic cohorts. We aimed to examine associations between neurocognition and functioning at baseline and over time. We used mixed effects models to investigate associations between neurocognitive test scores and longitudinal social and occupational functioning (“Social and Occupational Functioning Assessment Scale”) at 1–7 timepoints over five-years in 767 individuals accessing youth mental health services. Analyses were adjusted for age, sex, p..
View full abstractGrants
Awarded by Australian Government
Funding Acknowledgements
The authors gratefully thank the young people who have contributed to our research and to financial support from the Australian Government (Research Training Program Scholarship awarded to J.J.C.) and the National Health & Medical Research Council (Center of Research Excellence grant: No. 1061043; Australia Fellowship awarded to IBH: No. 511921).